Xtandi
(Enzalutamide)-
All Strengths
-
40mg
What is a generic medication?
Generic medications are significantly discounted copies of brand name medication that have the same active ingredients, intended use, dosage, side effects, effects, and route of administration as the original brand name medication. In other words, generic medications have the same pharmacological effects as their brand-name counterparts. Over half of all prescribed medications are for generic medications.
Who Should Take Xtandi?
Xtandi is a hormone therapy prescribed to men with advanced prostate cancer. Xtandi helps to slow the disease by preventing the action of male hormones in the body. A study of over a thousand men, sponsored by the drug’s manufacturer, found that Xtandi lowers the chance of cancer progressing by 83 percent. Xtandi is not for use in women.
Xtandi is a prescription medicine which needs to be taken exactly as indicated by a doctor or pharmacist. It comes in capsules of 40 mg. Patients are usually prescribed a dose consisting of four capsules which are to be taken with liquids once a day at the same time. Patients should not take more than one prescribed dose per day.
Important Safety Precautions
Patients who are sexually active need to use condoms or other forms of birth control as Xtandi may cause birth defects in children. It is important to use contraceptives during treatment with this medication and for the following three months.
In addition, patients taking Xtandi may be at higher risk of seizure and sudden loss of consciousness. Another potential risk is associated with the development of Posterior Reversible Encephalopathy Syndrome (PRES).
This condition is characterized by symptoms such as headaches, visual problems, confusion, and seizures. In the event a patient is experiencing any of these symptoms, Xtandi treatment must stop.
The most common side effect of Xtandi is fatigue. Patients may also experience back, muscle or bone pain, loss of appetite, digestion problems, vertigo, and hypertension.
The information above is a quick summary of facts about Xtandi, provided by third parties. Patients should always refer to a physician for medical advice on how to administer this drug and any other specific questions they may have.
Generic Alternatives to Xtandi
The active ingredient in Xtandi is called enzalutamide. It can slow the growth of cancerous tumors or even shrink them by preventing the male hormone testosterone from binding to testosterone receptors in prostate cancer cells. Scientists have discovered that testosterone encourages the growth of prostate cancer cells.
Xtandi is suitable for men who have stopped responding to other types of hormone therapy but have not yet had chemotherapy. It is also prescribed to patients who have completed chemotherapy with the drug docetaxel.
Generic alternatives to Xtandi are available for purchase through our online drug store.
Xtandi in the News
Xtandi Improves Survival in Patients with Metastatic Prostate Cancer
In an international clinical trial, hormone therapy with enzalutamide (the active ingredient in Xtandi), extended survival in men with metastatic prostate cancer. The article is a summary of a scientific paper first published in the New England Journal of Medicine.
Source: https://www.cancer.gov/types/prostate/research/enzalutamide-metastatic
Patent Denied, Price of Prostate Cancer Drug May Go Down
The Indian Patent Office has denied a patent to Xtandi, a drug used in prostate cancer. The refusal to grant a patent paves the way for the entry of drug's generic version at a fraction of the price, up to 70 percent cheaper.
The blockbuster drug which nets nearly $3 billion in worldwide sales, was acquired in August 2016 by Pfizer Inc as part of a deal when it bought Medivation, a biotech company. Medivation and Astellas jointly market Xtandi, with the latter selling the drug outside the US.
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