Inlyta Helps Treat the Following Conditions:

Kidney Cancer

Kidney cancer (also known as renal cancer) is a type of malignant tumor. Symptoms include fatigue, loss of appetite, weight loss, blood in the urine, low back pain, and lumps on the lower back.

While the causes of kidney cancer are not yet well-understood, factors like smoking, obesity, and high blood pressure are considered to play a role. Workplace exposure to certain toxic chemicals, as well as long-term use of certain medicines, are also considered risk factors.

Inlyta Active Ingredient

Inlyta targets advanced kidney cancer that has not responded to previous treatment. Inlyta contains the active ingredient axitinib which belongs to a class of drugs known as tyrosine kinase inhibitors.

Generic Inlyta Alternative

Generic alternatives to Inlyta are not yet available on this website.

General Drug Information

What is Inlyta and What Is It Used For?

Inlyta is prescribed to patients with advanced kidney cancer. It contains axitinib, a tyrosine kinase inhibitor, which slows or stops the growth of cancer cells.

Usage and Application

Before sourcing Inlyta online, please review thoroughly the medication guide provided by your doctor or pharmacist. Inform your physician of all other prescription medicines, over-the-counter drugs, and herbal supplements you are taking.

Inlyta should be taken exactly as prescribed, with dosage dependent on the patient’s medical condition and response to treatment. Patients who experience certain negative side effects may have their medication dose adjusted. Some patients may be asked to temporarily discontinue treatment.

Patients are usually directed to take Inlyta by mouth, with or without food. The medication is normally taken twice a day, with doses scheduled twelve hours apart.

Each tablet should be swallowed whole, with a glass of water. Do not split or crush tablets.

Patients who vomit their dose of Inlyta should not take an additional dose. Take your next dose at your regular scheduled time. Never take two doses at the same time.

Grapefruit increases the risk of Inlyta side effects. Patients should avoid eating grapefruit and drinking grapefruit juice while using Inlyta unless told otherwise by their doctor or pharmacist. Ask your doctor or pharmacist for more information.

Do not increase your dose or use Inlyta for longer or more often than prescribed. This is unlikely to bring about a faster improvement, however, your risk of serious side effects will increase.

Patients should use Inlyta regularly to experience its full benefit. To prevent forgetting, take this medication at the same time each day.

Inlyta can be absorbed through the skin and lungs and can harm an unborn baby. Women who are pregnant – or who may become pregnant – should not handle this medication or breathe dust from the tablets.

Considerations Before Taking Inlyta

Before starting treatment, patients should discuss the possibility of allergic reactions to Inlyta. It is very important to discuss the patient’s medical history, especially relating to liver disease, kidney disease, and high blood pressure.

Patients should also report any bleeding or clotting problems (e.g. bleeding from stomach ulcers), as well as cancer that has spread to the brain and has not been treated.

Inlyta may make patients more prone to getting infections and/or exacerbate any current infections. To prevent the spread of infection, patients should wash their hands well and avoid contact with those who have contagious infections (e.g. chicken pox, measles, the flu). Contact your doctor if you believe you have been exposed to an infection.

Patients should not receive any vaccinations without the consent of their doctor. Avoid contact with people who have recently received live vaccines (e.g. flu vaccine inhaled through the nose).

Inlyta may cause dizziness. Alcohol and marijuana can exacerbate this effect. Do not drive, use machinery, or perform tasks which require alertness until you can do so safely. Limit alcoholic beverages and discuss marijuana use with your doctor.

Patients preparing for surgery or certain dental procedures should inform their doctor or dentist about all drugs, supplements, and herbal products they are taking. Inlyta should not be taken least 24 hours before any planned surgical procedures.

Inlyta can be absorbed through the skin and lungs and may harm an unborn baby. Women who are pregnant (or who may become pregnant) should never handle this medication or inhale the dust from the tablets.

This drug is not recommended for use during pregnancy. Both male and female patients using Inlyta must use reliable forms of birth control during treatment. In the event of pregnancy, couples should contact their doctor immediately, regardless of whether the woman or partner is taking Inlyta.

It is unknown whether Inlyta passes into breast milk, so breastfeeding while taking this medication is not recommended. Women should consult their doctor for more details.

Delayed and Omitted Doses

To maximize the efficacy of treatment, patients should take each dose of Inlyta exactly as scheduled. Patients who miss a dose of Inlyta should contact their doctor or pharmacist immediately to establish a new dosing schedule. Do not double your dose to catch up.

Other Medications and Inlyta

Drug interactions may alter the way Inlyta works, increasing the risk of negative side effects. Before starting treatment, patients should discuss all medications and supplements they are taking with their doctor. Patients should always adhere to their dose. Do not stop taking this medication unless advised otherwise by your doctor.

Certain medications affect the removal of Inlyta from the body, changing the way it works. Examples include azole antifungals (e.g. itraconazole, voriconazole, ketoconazole), macrolide antibiotics (e.g. clarithromycin) and rifamycin antibiotics (e.g. rifampin, rifabutin, rifapentine).

HIV protease inhibitors (e.g. ritonavir, atazanavir, nelfinavir, saquinavir, and indinavir) have the same effect. Additional examples include anticonvulsants – like phenytoin, carbamazepine, and phenytoin – as well as the herb St. John's wort.

Possible negative interactions may occur with the antidepressant nefazodone, antibiotic telithromycin, and bosentan, which is prescribed to treat pulmonary artery hypertension. HIV medications etravirine and efavirenz have a similar effect, as does the antibiotic nafcillin. Additional examples include the sleep medication modafinil and the corticosteroid hormone dexamethasone.

This is not a full list of all possible interactions. Please consult your physician before purchasing Inlyta.

Adverse Reactions

Patients are prescribed this medication because their doctor has judged that the benefits of treatment are greater than the risks. Most patients use Inlyta without serious side effects.

Common side effects, however, include nausea, vomiting, loss of appetite, dizziness, tiredness, and weakness. Some patients may also experience weight loss, temporary hair loss, cough, hoarseness, and headache.

Additional symptoms include upset stomach, constipation, and an altered sense of taste. Patients should alert their physician should these symptoms persist or worsen.

Diarrhea is a common side effect that can cause serious dehydration. Patients should drink plenty of fluids and contact their doctor immediately if they experience the following symptoms: dizziness, lightheadedness, excessive thirst, and unusual dry mouth.

Serious Side Effects

Serious side effects include unusual tiredness, shortness of breath, muscle and/or joint pain, and the swelling of the ankles, feet and/or hands. Some patients may experience easy bruising or bleeding, manifesting in nose bleeds, gum bleeds, and pink or dark urine.

Patients should monitor for signs of kidney problems (e.g. change in the amount of urine). Contact your doctor immediately if you experience thyroid malfunction symptoms: unusual tiredness, irregular heartbeat, unusual weight gain or loss, and cold/heat intolerance.

It is also important to monitor for sores in the mouth or throat. Redness, blisters, swelling, and pain in the palms of the hands/soles of the feet are also possible.

Inlyta may lower a patient’s ability to fight infections, making them more prone to new infections. It can also exacerbate infections that already exist. Patients should contact their doctor immediately if they experience signs of infection (e.g. fever, chills, and persistent sore throat).

Inlyta may raise blood pressure. Patients should check your blood pressure regularly and inform their doctor if the results are high. Some patients may have to take medication to control their blood pressure levels.

In rare cases, Inlyta may cause reversible posterior leukoencephalopathy syndrome (RPLS). This is a serious condition which can present the following symptoms: a persistent headache, seizures, sudden vision changes, confusion, and other mental changes.

Inlyta rarely causes serious (possibly fatal) blood clots, raising the risk of stroke, heart attack, pulmonary embolism, deep vein thrombosis, and retinal vein or artery occlusion. Blood clot risk is higher for patients who are severely dehydrated, immobile (e.g. after long plane trips), or bedridden.

Patients with a history of blood clots, heart disease, blood vessel disease, heart failure, and stroke also face an increased risk of developing dangerous blood clots. The same applies to patients who use estrogen-containing products.

Get immediate medical help in the event of the following symptoms: confusion, dizziness, fainting, unusual sweating, shortness of breath, rapid breathing, and pain in the chest, jaw and/or left arm. Additional symptoms include sudden vision changes, severe headaches, slurred speech, weakness on one side of the body, and pain, swelling, or warmth in the groin and/or calves.

Patients should seek immediate medical help in the event of severe and persistent stomach pain, bloody or black stools, and vomit that looks like coffee grounds.

Allergic Reactions

Inlyta may cause a mild to moderate rash that is usually not serious. However, patients may not be able to tell this rash apart from one that signifies a severe reaction. Therefore, it’s best to inform your doctor immediately in the event of any rash.

Serious allergic reactions to Inlyta are rare, yet patients should be aware of symptoms including rash, throat and/or tongue itching and swelling, severe dizziness, and trouble breathing.

How to Store Inlyta

Inlyta should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep away from children and pets.

Unwanted medication should be disposed of properly and should not be poured into drains or flushed down the toilet. Patients should consult a pharmacist or their local waste disposal company to find out more about safe disposal methods.