Stendra

The active ingredient in Stendra is avanafil.

Avanafil is part of the phosphodiesterase type 5 enzyme inhibitor drug class. It helps increase blood flow to the penis during sexual stimulation by blocking the PDE5 enzyme that breaks down cGMP. When cGMP levels stay higher, the blood vessels in the penis relax, allowing more blood to enter. This leads to an erection when sexual stimulation is present. Avanafil only works with sexual activity and does not increase sexual desire.

Follow all directions given to you by your doctor and read all documents provided, including the full Prescribing Information, FDA-Approved Product Labeling, Instructions for Use, and Medication Guide before using Stendra. However, the following is a synopsis of the general guidelines for the use of Stendra:

• Stendra is usually taken 30 minutes before sexual activity, although some patients may be instructed to take it as early as 15 minutes before.
• Do not take Stendra more than once per day.
• Sexual stimulation is required for Stendra to work.
• You may take Stendra with or without food, but high-fat meals may delay how fast it works.
• Avoid drinking alcohol when taking Stendra, as this may increase the risk of low blood pressure and dizziness.

Some mild or common side effects of Stendra seen in clinical trials as compared to placebo include:

• Headache.
• Flushing.
• Nasal congestion.
• Back pain.
• Lightheaded feeling.
• Upset stomach.

Some individuals may experience serious side effects while using Stendra. These side effects may require immediate medical attention. If you experience any of the following, contact your healthcare provider or seek emergency medical help:

• Sudden vision loss may indicate a serious eye problem.
• Sudden hearing loss or tinnitus.
• Chest pain or signs of a heart attack.
• Severe dizziness or fainting from very low blood pressure.
• Priapism, a prolonged erection lasting more than four hours or a painful erection.
• Symptoms of an allergic reaction include hives, swelling, or trouble breathing.

These are not all of the possible side effects of Stendra. You should always seek medical advice from your healthcare provider for any questions or concerns about your medical condition or treatment. Read all patient information, medication guides, or drug information sheets that come with this medication. You can also report adverse effects to the Food and Drug Administration at www.fda.gov/medwatch or 1-800-FDA-1088.

Before starting Stendra, it is crucial to discuss any existing health conditions with your healthcare provider. You should be sure that your healthcare provider is aware of all your medical conditions, including:

Heart disease, heart failure, or a history of heart attack.

High blood pressure or hypertension that is not controlled.

Angina or chest pain.

Retinitis pigmentosa.

Peyronie’s disease or anatomical deformities of the penis.

Blood disorders such as leukemia or sickle cell anemia.

Any heart problems where sexual activity is unsafe.

A history of low blood pressure or episodes of feeling lightheaded.

Use of any form of nitrates, including nitroglycerin, isosorbide dinitrate, or recreational nitrate “poppers.”

Use of riociguat.

Known hypersensitivity to avanafil or any components of the tablet.

Situations where sexual activity is not recommended due to heart problems.

Some men may notice effects of avanafil as soon as 15 minutes after taking a dose, although many are advised to take it 30 minutes before sexual activity. The medication works only in the presence of sexual stimulation.

When Stendra is taken with other prescription drugs, over-the-counter medications, vitamins, and supplements, it may change how they work or increase the frequency or severity of side effects. Make sure that you tell your healthcare professional about anything that you are taking to avoid any negative drug interactions, including:

Nitrates such as nitroglycerin or isosorbide.

Alpha blockers, including tamsulosin or doxazosin.

Blood pressure medicines that may increase the risk of low blood pressure.

PDE5 inhibitors such as sildenafil, tadalafil, or vardenafil.

Medications that affect liver enzyme activity, including ritonavir, erythromycin, clarithromycin, itraconazole, and ketoconazole.

Riociguat.

Medicines for heart problems or hypertension.

Grapefruit juice, which may increase avanafil levels.

Alcohol can worsen hypotension.

Stendra is available in 50 mg, 100 mg, or 200 mg tablets.

It should be stored at room temperature out of reach of children or pets.

Stendra is manufactured by Vivus, Inc.

Yes, it is available from many manufacturers of generic drugs.

You can stop taking Stendra whenever you choose, as it is taken only when needed for sexual activity. However, if you have concerns about side effects, drug interactions, or changes in your health, consult your healthcare provider for medical advice.

This medication should only be used in males.

This medication should only be used in males.