Sulfasalazine EC
(Sulfasalazine EC)Sulfasalazine EC Overview
Sulfasalazine is used to treat a certain type of bowel disease called ulcerative colitis. Sulfasalazine EC does not cure this condition, but it helps decrease symptoms such as fever, stomach pain, diarrhea, and rectal bleeding. After an attack is treated, sulfasalazine is also used to increase the amount of time between attacks. Sulfasalazine EC works by reducing irritation and swelling in the large intestines. In addition, delayed-release tablets of sulfasalazine are used to treat rheumatoid arthritis. Sulfasalazine helps to reduce joint pain, swelling, and stiffness. Early treatment of rheumatoid arthritis with sulfasalazine helps to reduce/prevent further joint damage so you can do more of your normal daily activities. Sulfasalazine EC is used with other drugs, rest, and physical therapy in patients who have not responded to other medications (salicylates, nonsteroidal anti-inflammatory drugs-NSAIDs).
How to Use Sulfasalazine EC
Take Sulfasalazine EC by mouth after meals with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. To prevent stomach upset, your doctor may recommend a slow increase in your dosage when starting treatment. Dosage of Sulfasalazine EC is based on your medical condition and response to therapy. In children, Dosage of Sulfasalazine EC is also based on weight. If you are taking the delayed-release tablets, swallow them whole. Do not crush, chew, or break the tablets. Doing so may increase the chance of stomach upset. Drink plenty of fluids during treatment with Sulfasalazine EC unless otherwise directed by your doctor. This will help prevent kidney stones. Take Sulfasalazine EC regularly to get the most benefit from it. To help you remember, take it at the same times each day. Inform your doctor if your condition does not improve or if it worsens. For the treatment of rheumatoid arthritis, it may take 1-3 months before you notice any improvement in your symptoms.
Sulfasalazine EC Precautions
Before taking sulfasalazine, tell your doctor or pharmacist if you are allergic to it; or to sulfa drugs; or to aspirin and related drugs (salicylates, NSAIDs such as ibuprofen); or to mesalamine; or if you have any other allergies. Sulfasalazine EC may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Sulfasalazine EC, tell your doctor or pharmacist your medical history,intestinal blockage, urinary blockage, kidney disease, liver disease, blood disorders (such as aplastic anemia, porphyria), a certain genetic condition (G6PD deficiency), asthma, severe allergies, current/recent/returning infections. Sulfasalazine EC may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Sulfasalazine EC may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Get medical help right away if you get sunburned or have skin blisters/redness. Sulfasalazine EC is similar to aspirin. Children and teenagers younger than 18 years should not take aspirin or aspirin-related medications (such as salicylates) if they have chickenpox, flu, or any undiagnosed illness, or if they have just been given a live virus vaccine (such as varicella vaccine), without first consulting a doctor about Reye's syndrome, a rare but serious illness. Sulfasalazine EC can temporarily affect fertility in males. Ask your doctor for more details. During pregnancy, Sulfasalazine EC should be used only when clearly needed. Caution is advised if Sulfasalazine EC is used near the expected delivery date because similar drugs may cause harm to a newborn. Discuss the risks and benefits with your doctor. If you become pregnant while taking Sulfasalazine EC, contact your doctor right away. Sulfasalazine EC may lower your folic acid levels, increasing the risk of spinal cord defects. Check with your doctor to make sure you are taking enough folic acid. Prenatal care should include tests for spinal cord defects. Sulfasalazine EC passes into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Sulfasalazine EC Misdose
If you miss a dose of Sulfasalazine EC, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Sulfasalazine EC Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.digoxin, folic acid, methenamine, PABA taken by mouth. Sulfasalazine is very similar to mesalamine. Do not use mesalamine medications taken by mouth while using sulfasalazine. Sulfasalazine EC may interfere with certain lab tests (such as urine normetanephrine levels, liver function tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use Sulfasalazine EC.
Sulfasalazine EC Side Effects
Stomach upset, nausea, vomiting, loss of appetite, headache, dizziness, or unusual tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Sulfasalazine EC may cause your skin and urine to turn orange-yellow. This effect is harmless and will disappear when the medication is stopped. Rarely, delayed-release tablets of sulfasalazine may appear whole or only partly dissolved in your stool. If this occurs, tell your doctor right away so your treatment can be changed. Remember that Sulfasalazine EC has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Sulfasalazine EC do not have serious side effects. Tell your doctor right away if you have any serious side effects,hearing changes (such as ringing in the ears), mental/mood changes, signs of kidney problems (such as change in the amount of urine, painful urination, blood in the urine), new lump/growth in the neck (goiter), numbness/tingling of the hands/feet, signs of low blood sugar (such as hunger, cold sweat, blurred vision, weakness, fast heartbeat). Sulfasalazine EC may rarely cause very serious allergic reactions (such as Stevens-Johnson syndrome), blood disorders (such as agranulocytosis, aplastic anemia), liver damage, nerve/muscle problems and infections. Get medical help right away if you have any very serious side effects,headache that is severe or doesn't go away, skin rash/blisters/peeling, mouth sores, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, chest pain, signs of infection (such as sore throat that doesn't go away, fever, chills, cough), swollen lymph nodes, easy bruising/bleeding, severe tiredness, muscle pain/weakness (especially with fever and unusual tiredness), pale or blue skin/lips/nails, new/worsening joint pain, confusion, unexplained neck stiffness, seizures, signs of liver problems (such as nausea/vomiting that doesn't stop, severe stomach/abdominal pain, yellowing eyes/skin, dark urine). This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Sulfasalazine EC Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Sulfasalazine EC when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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