Memantine
(Memantine)Memantine Overview
Memantine is used to treat moderate to severe confusion (dementia) related to Alzheimer's disease. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions. Memantine works by blocking the action of a certain natural substance in the brain (glutamate) that is believed to be linked to symptoms of Alzheimer's disease.
How to Use Memantine
Read the Patient Information Leaflet if available from your pharmacist before you start taking memantine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Memantine by mouth with or without food as directed by your doctor. The Dosage of Memantine is based on your medical condition and response to treatment. When you first start taking Memantine, you will usually take it once daily. To reduce your risk of side effects, your doctor may direct you to start Memantine at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Once your dose increases to more than 5 milligrams per day, take Memantine twice daily or as directed by your doctor. If you are taking memantine oral liquid, read the manufacturer's instruction sheet that comes with the bottle. Follow the directions exactly. Use the oral syringe that comes with the product to measure out your dose. Do not use a household spoon because you may not get the correct dose. Swallow the medication directly from the syringe. Do not mix it with water or other liquids. Rinse the syringe with water after each use. Consult your doctor or pharmacist if you have any questions. Use Memantine regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. Tell your doctor if your condition worsens.
Memantine Precautions
Before taking memantine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Memantine may contain inactive ingredients which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Memantine, tell your doctor or pharmacist your medical history,kidney problems, severe urinary tract infections, recent dietary change (from a high-protein diet to a vegetarian diet). Memantine may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, Memantine should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if Memantine passes into breast milk. Consult your doctor before breast-feeding.
Memantine Misdose
If you miss a dose of Memantine, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. If you forget to take memantine for several days, talk to your doctor before your next dose. You may need to start at a lower dose again and slowly increase it.
Memantine Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.carbonic anhydrase inhibitors (such as acetazolamide, methazolamide), sodium bicarbonate.
Memantine Side Effects
Body aches, dizziness, constipation, and headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that Memantine has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Memantine do not have serious side effects. A very serious allergic reaction to Memantine is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Memantine Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Memantine when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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