Kalydeco Helps Treat the Following Conditions:

Cystic Fibrosis

Cystic fibrosis is a genetic disorder of the lungs, digestive tract, and other systems in the body. Patients with the disease have two copies of the CFTR gene which have mutations. Some people are carriers of the CFTR gene mutation but do not have the disease.

Cystic fibrosis affects the cells producing mucus and other fluids in the body. In patients, these secretions are thick and often obstruct the lung passageways. Symptoms may vary, common symptoms include wheezing, difficulties breathing, frequent lung infections, intestinal blockage, and severe constipation. The disease dramatically affects life expectancy.

Kalydeco Active Ingredient

Kalydeco contains the active ingredient ivacaftor, which is prescribed to patients with cystic fibrosis who have particular mutations in the CFTR gene.

Generic Kalydeco Alternative

Generic alternatives to Kalydeco are not yet available on this website.

General Drug Information

What is Kalydeco and What Is It Used For?

Kalydeco is prescribed to patients with cystic fibrosis who have certain abnormal CFTR gene mutations. In these patients, Kalydeco may help improve symptoms of wheezing and breathlessness, reduce the risk of lung infections, and improve weight gain.

Usage and Application

Before sourcing Kalydeco online, please review thoroughly the medication guide provided by your doctor or pharmacist. Inform your physician of all other prescription medicines, over-the-counter drugs, and herbal supplements you are taking.

Kalydeco should be taken exactly as prescribed. The dosage depends on the patient’s medical condition, age, weight, response to treatment, and other medications they may be taking.

Patients are usually directed to take Kalydeco orally twice a day, with doses scheduled twelve hours apart. Those who are using the tablet form of Kalydeco should take it with foods which are high in fat (e.g. eggs, butter, peanut butter, cheese).

Patients who have been prescribed the granule form of Kalydeco should gently shake the packet before use. Empty the packet into a small cup with one teaspoonful (5 milliliters) of either liquids or soft food – like yogurt or applesauce – which is at or below room temperature.

Consume the entire mixture within one hour, and eat food with high-fat content either just before or after taking the mixture.

Patients should use Kalydeco regularly to experience its full benefit. To prevent forgetting, take this medication at the same time each day.

Grapefruit, grapefruit juice, and Seville oranges (ie. in marmalade) increase the risk of side effects for Kalydeco patients. Ask your doctor or pharmacist for more information.

Patients should inform their doctor in the event their condition fails to improve or worsens.

Considerations Before Taking Kalydeco

Before starting treatment, patients should discuss the possibility of allergic reactions to Kalydeco. It is very important to discuss the patient’s medical history, especially relating to liver disease.

Kalydeco may cause dizziness. Alcohol and marijuana can exacerbate this effect. Do not drive, use machinery, or perform tasks which require alertness until you can do so safely. Limit alcoholic beverages and discuss marijuana use with your doctor.

Patients preparing for surgery or certain dental procedures should inform their doctor or dentist about all drugs, supplements, and herbal products they are taking.

Kalydeco should be used only when clearly needed during pregnancy. Female patients should discuss the risks and benefits of treatment with their doctor.

It is unknown whether Kalydeco passes into breast milk. Women should consult their doctor before breastfeeding.

Delayed and Omitted Doses

Patients who miss a dose of Kalydeco should take it as soon as they remember. If this happens less than six hours until the next scheduled dose, patients should skip the missed dose and proceed as usual. Do not double the dose to catch up.

Other Medications and Kalydeco

Drug interactions may alter the way Kalydeco works, increasing the risk of negative side effects. Before starting treatment, patients should discuss all medications and supplements they are taking with their doctor. Patients should always adhere to their dose. Do not stop taking this medication unless advised otherwise by your doctor.

Certain medications can affect the removal of Kalydeco from the body, changing the way it works. Examples include rifamycin antibiotics (e.g. rifabutin) and anticonvulsants (e.g. carbamazepine, phenytoin). St. John's wort has the same effect.

This is not a full list of all possible interactions. Please consult your physician before purchasing Kalydeco online.

Adverse Reactions

Patients are prescribed this medication because their doctor has judged that the benefits of treatment are greater than the risks. Most patients use Kalydeco without serious side effects.

Common side effects can include nausea, dizziness, and headache. Patients should alert their physician should these symptoms persist or worsen.

Patients should immediately contact their doctor in the event they experience any vision changes.

In rare cases, Kalydeco may cause serious liver disease. Seek immediate medical help in the event of the following symptoms: dark urine, persistent nausea, vomiting, loss of appetite, stomach pain, and yellowing of the eyes and/or skin.

Kalydeco may cause a rash that is usually not serious. It may be difficult to tell this rash apart from one signifying a severe reaction. Inform your doctor immediately if rash symptoms occur.

Serious allergic reactions to Kalydeco are rare, yet patients should be aware of symptoms including rash, itching and swelling (throat/tongue), severe dizziness, and trouble breathing.

How to Store Kalydeco

Kalydeco should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep away from children and pets.

Unwanted medication should be disposed of properly and should not be poured into drains or flushed down the toilet. Patients should consult a pharmacist or their local waste disposal company to find out more about safe disposal methods.