Buspirone
(Buspirone)Buspirone Overview
Buspirone is used to treat anxiety. It may help you think more clearly, relax, worry less, and take part in everyday life. It may also help you to feel less jittery and irritable, and may control symptoms such as trouble sleeping, sweating, and pounding heartbeat. Buspirone is a medication for anxiety (anxiolytic) that works by affecting certain natural substances in the brain (neurotransmitters).
How to Use Buspirone
Take Buspirone by mouth as directed by your doctor, usually 2 or 3 times a day. You may take Buspirone with or without food, but it is important to choose one way and always take it the same way so that the amount of drug absorbed will always be the same. Buspirone may come in a tablet that can be split to get the correct dose for you. Follow the manufacturer's Patient Instruction Sheet or ask your pharmacist how to split the tablet to get your dose. Avoid eating grapefruit or drinking grapefruit juice while taking Buspirone unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Dosage of Buspirone is based on your medical condition and response to therapy. Use Buspirone regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. When Buspirone is started, symptoms of anxiety (such as restlessness) may sometimes get worse before they improve. It may take up to a month or more to get the full effect of Buspirone. Inform your doctor if your symptoms last or get worse.
Buspirone Precautions
Before taking buspirone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Buspirone may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Buspirone, tell your doctor or pharmacist your medical history,kidney problems, liver problems, bipolar disorder (manic-depression), Parkinson's disease. Buspirone may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). If you are taking other medications for anxiety, do not suddenly stop them unless directed by your doctor. Buspirone will not prevent withdrawal symptoms from other medications, and your dose may need to be lowered slowly when you switch to buspirone. Discuss your treatment plan with your doctor. If you experience withdrawal symptoms, tell your doctor right away. During pregnancy, Buspirone should only be used when clearly needed. Tell your doctor if you are pregnant before using Buspirone. Discuss the risks and benefits with your doctor. It is unknown if Buspirone passes into breast milk. However, similar drugs pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.
Buspirone Misdose
If you miss a dose of Buspirone, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Buspirone Interactions
See also How to Use section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.antidepressants (including SSRIs such as fluoxetine, tricyclic antidepressants such as amitriptyline/nortriptyline, trazodone), haloperidol. Taking MAO inhibitors with Buspirone may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with Buspirone. Most MAO inhibitors should also not be taken for two weeks before and after treatment with Buspirone. Ask your doctor when to start or stop taking Buspirone. Other medications can affect the removal of buspirone from your body, which may affect how buspirone works. Examples include azole antifungals (such as itraconazole), corticosteroids (such as dexamethasone), diltiazem, nefazodone, rifamycins (such as rifabutin), ritonavir, drugs used to treat seizures (such as phenytoin, phenobarbital), among others. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Buspirone may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use Buspirone.
Buspirone Side Effects
Dizziness, drowsiness, headache, nausea, nervousness, lightheadedness, restlessness, blurred vision, tiredness, and trouble sleeping may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly. Remember that Buspirone has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Buspirone do not have serious side effects. Rarely, patients taking buspirone may develop movement disorders such as shakiness (tremors), muscle stiffness, mask-like facial expression, jerky walking movements, or a condition known as tardive dyskinesia. In some cases, these conditions may be permanent. Tell your doctor right away if you develop any unusual/uncontrolled movements (especially of the face, mouth, tongue, arms, or legs). Get medical help right away if you have any very serious side effects,easy bleeding/bruising, shortness of breath, chest pain, fast/irregular heartbeat. A very serious allergic reaction to Buspirone is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist . Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Buspirone Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Buspirone when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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