Bupropion SR
(Bupropion SR)Bupropion SR Overview
Bupropion SR is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.
Bupropion SR Warnings
Bupropion is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience new or worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication, even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice new or worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. If you are using bupropion to quit smoking and experience any of these symptoms, stop taking it and contact your doctor right away. Also, tell your doctor right away if you have any of these symptoms after stopping treatment with bupropion.
How to Use Bupropion SR
Read the Medication Guide provided by your pharmacist before you start using bupropion and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take Bupropion SR by mouth with or without food as directed by your doctor, usually twice a day. If you have stomach upset, you may take Bupropion SR with or after a meal or snack. Take the first dose as soon as you wake up in the morning and the second dose at least 8 hours later, or take as directed by your doctor. Taking Bupropion SR late in the day may cause trouble sleeping (insomnia). Take Bupropion SR regularly to get the most benefit from it. To help you remember, take it at the same times each day. Swallow the tablets whole. Do not crush or chew the tablets. Doing so can release all of the drug at once, increasing the risk of side effects. The Dosage of Bupropion SR is based on your medical condition, liver function, and response to treatment. To reduce your risk of side effects, your doctor may direct you to start Bupropion SR at a low dose and gradually increase your dose. Do not increase your dose or use Bupropion SR more often or for longer than prescribed. Your condition will not improve any faster and your risk of side effects will increase. Do not stop taking Bupropion SR without consulting your doctor. Your dose may need to be gradually decreased. It may take 4 weeks or longer before you get the full benefit of Bupropion SR. Tell your doctor if your condition does not improve or if it worsens.
Bupropion SR Precautions
Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Bupropion SR may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Bupropion SR, tell your doctor or pharmacist your medical history,diabetes, heart disease, high blood pressure, kidney problems, liver disease, use/abuse of drugs/alcohol, seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumor, eating disorders such as bulimia/anorexia nervosa), personal or family history of glaucoma (angle-closure type). Bupropion SR should not be used if you are suddenly stopping regular use of sedatives (including benzodiazepines such as lorazepam), drugs used to treat seizures, or alcohol. Doing so may increase your risk of seizures. Bupropion SR may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Alcohol can also increase your risk of seizures. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of Bupropion SR, especially dizziness and memory loss. Dizziness can increase the risk of falling. During pregnancy, Bupropion SR should be used only when clearly needed. Since untreated mental/mood problems (such as depression, seasonal affective disorder, bipolar disorder) can be a serious condition, do not stop taking Bupropion SR unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using Bupropion SR during pregnancy. Bupropion SR passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Bupropion SR Misdose
If you miss a dose of Bupropion SR, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Bupropion SR Interactions
See also Precautions section. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.codeine, pimozide, tamoxifen, thioridazine. Taking MAO inhibitors with Bupropion SR may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with Bupropion SR. Most MAO inhibitors should also not be taken for two weeks before and after treatment with Bupropion SR. Ask your doctor when to start or stop taking Bupropion SR. Bupropion SR may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease, urine screening for amphetamines), possibly causing false results. Tell laboratory personnel and all your doctors you use Bupropion SR.
Bupropion SR Side Effects
Dry mouth, sore throat, dizziness, nausea, vomiting, ringing in the ears, headache, decreased appetite, weight loss, constipation, trouble sleeping, increased sweating, or shaking (tremor) may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. An empty tablet shell may appear in your stool. This effect is harmless because your body has already absorbed the medication. Remember that Bupropion SR has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using Bupropion SR do not have serious side effects. Bupropion SR may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Tell your doctor right away if you have any serious side effects,fast/pounding/irregular heartbeat, mental/mood changes (such as anxiety, agitation, confusion, unusual behavior/thinking, memory loss), unusual weight loss or gain. Get medical help right away if you have any very serious side effects,seizure, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night, blurred vision). A very serious allergic reaction to Bupropion SR is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Bupropion SR Storage
Store at room temperature away from light and moisture. You may notice an odor from the tablets; this is normal and does not affect how they work. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Bupropion SR when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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