What medical conditions does Mounjaro treat?
Type 2 diabetes (T2DM)
According to the Centers for Disease Control and Prevention (CDC), there are over 37 million people in the United States that have diabetes (about 1 in 10). Of these 37 million people, between 90% to 95% have type 2 diabetes (T2DM). T2DM is due to your body not properly using insulin to fully absorb and use the sugar (glucose) from the food you eat. Over time, your pancreas becomes exhausted and can not make enough insulin, which results in high blood sugar levels (hyperglycemia). T2DM is typically treated with medications along with diet and exercise.
What is the active ingredient in Mounjaro?
Generic equivalent of Mounjaro: tirzepatide
Mounjaro is an FDA-approved prescription medication that is manufactured by Eli Lilly and Company. The active ingredient in Mounjaro is tirzepatide. Tirzepatide belongs to a class of medications called glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonists. It works by acting like GLP and GLP-1 hormones that are released in your gut after eating which helps regulate your blood sugar. These hormones cause your pancreas to produce more insulin while preventing your liver from making more sugar. Tirzepatide also slows how fast you digest food which helps you eat less. All of this helps you reduce your blood sugar levels.
General Drug Information
What is Mounjaro and what is it used for?
Mounjaro is an injectable diabetes medication that is used along with diet and exercise to treat type 2 diabetes. It should not be used if you have a history of pancreatitis and it is not approved to treat type 1 diabetes (T1DM).
Monjauro is available as an injection in strengths of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg per 0.5 ml in a single-dose pen.
How do you use Mounjaro?
Read the Instructions for Use that come with this medication.
You should use Mounjaro exactly as your doctor prescribes it. Do not change your dose or stop taking this medication without discussing it with them first.
Mounjaro is typically injected subcutaneously (under your skin) in your stomach, thigh, or upper arm. You should inject Mounjaro once a week on the same day each week. You can inject this medication at any time of the day, with or without food.
You can change the day of your Mounjaro injection as long as there are at least 3 days (72 hours) between the 2 injections.
You should not mix Mounjaro and insulin in the same injection. You can administer Mounjaro and insulin in the same area of the body, but not next to each other.
Change your injection site each week. Do not use the same site for each Mounjaro injection.
Labs such as kidney function, fasting blood glucose, and hemoglobin A1c (HgA1c) should be performed while on Mounjaro. Be sure to keep all medical and lab appointments.
Oral birth control pills may not work as well while on Mounjaro. You may need a second form of birth control for 4 weeks after starting this medication and for 4 weeks after any dose increase. Talk to your doctor about forms of birth control that may be right for you while on Mounjaro.
Before taking Mounjaro
You should not take Mounjaro if you have a known allergy to tirzepatide or any inactive ingredient in this product’s formulation.
You should also be sure your healthcare provider is aware of your medical history, including:
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History of pancreas or kidney problems
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History of severe stomach problems such as gastroparesis (delayed emptying of your stomach) or other digestion problems
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History of diabetic retinopathy
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Personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) or multiple endocrine neoplasias (MEN2) syndrome
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Are pregnant, plan on becoming pregnant, or are breastfeeding
What do you do if you miss a dose of Mounjaro?
If you miss a dose of this medication, take it as soon as you remember, as long it is within 4 days (96 hours) after the missed dose. If it has been more than 4 days (96 hours), skip the missed dose and administer your next Mounjaro injection on its next scheduled day. You should NOT take 2 doses of Mounjaro within 3 days (72 hours) of each other.
Mounjaro drug interactions
When Mounjaro is taken with other medications, it can change the way they work or increase the frequency and severity of side effects. You should discuss with a healthcare professional whether any of the prescription drugs, over-the-counter medications, vitamins, and herbal supplements you take may interact with this medication.
Mounjaro slows down how fast your stomach empties so it can affect oral medications that are taken along with it. You should be closely monitored if you are taking medications that have a narrow therapeutic index such as Coumadin (warfarin). Mounjaro may also decrease the effectiveness of oral birth control pills. Discuss with your doctor other methods of birth control that you may need while on this medication.
Mounjaro side effects
Some common side effects of Mounjaro include:
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Nausea
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Diarrhea
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Decreased appetite
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Weight loss
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Upset stomach
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Constipation
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Stomach pain
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Vomiting
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Injection site reactions
Mounjaro can sometimes cause more serious side effects including:
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Serious allergic reactions, including hives, swelling of your throat and tongue, or trouble breathing
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Severe low blood sugar (hypoglycemia), especially if taken along with sulfonylureas or insulin
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Increased risk of thyroid cancer or thyroid C-cell tumors
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Pancreatitis (inflammation of your pancreas)
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Worsening diabetic retinopathy
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Kidney dysfunction
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Gallbladder problems including gallstones
This is not a full list of the side effects of this medication. Contact your healthcare provider for medical advice about any possible side effects you experience while taking Mounjaro. You can also report your adverse reactions to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
How to store Mounjaro
Store your Mounjaro single-use pens in the original carton in the refrigerator between 36⁰F to 46⁰F (2⁰C to 8⁰C). You can store each single-use pen at room temperature up to 86⁰F (30⁰C) for up to 21 days if needed. Do not freeze Mounjaro or use it if it has been frozen.
How much does Mounjaro cost?
Mounjaro is an expensive brand-name medication that has no available generic. Check out Universal Drugstore’s online pharmacy for the lowest price available on this and many other medications, no coupon or savings card is needed!
Mounjaro alternatives
Sources:
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Mounjaro Package Insert: https://uspl.lilly.com/mounjaro/mounjaro.html#pi
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Mounjaro Medication Guide: https://uspl.lilly.com/mounjaro/mounjaro.html#mg
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Medscape: https://reference.medscape.com/drug/mounjaro-tirzepatide-4000264#4